Nardil (Phenelzine)

Overview
Nardil is a prescription drug approved by the Food and Drug Administration (FDA) to treat certain types of depression when other antidepressants have failed. Nardil is also known by its drug name, Phenelzine.… read more

Neurontin (Gabapentin)

Overview
Neurontin is a prescription drug approved by the Food and Drug Administration (FDA) to treat postherpetic neuralgia and some types of seizures. Neurontin is sometimes prescribed to treat depression and anxiety.… read more

Oleptro (Trazodone) for Depression

The Oleptro brand name has been discontinued in the U.S. for reasons unrelated to safety or efficacy. Other brand names or generic alternatives may be available. If you’re currently taking this medication, talk to your… read more

Parnate (Tranylcypromine)

Overview
Parnate is a prescription drug approved by the Food and Drug Administration (FDA) to treat major depressive episodes in adults under close medical supervision. Parnate is also known by its drug name,… read more

ProlivRx for Depression

Overview
ProlivRx is a prescription-only neuromodulation device approved by the U.S. Food and Drug Administration (FDA) as an adjunctive (add-on) treatment for adults with major depressive disorder (MDD) who have not had…

Provigil (Modafinil)

Overview
Provigil is a prescription medication approved by the Food and Drug Administration (FDA) for the treatment of excessive sleepiness associated with narcolepsy, obstructive sleep apnea, and shift work disorder.… read more

Psychotherapy

Overview
Psychotherapy, also known simply as therapy, is a common treatment for depression. Therapy may be used to treat depression on its own or in combination with antidepressant medications.

What does it involve?… read more

Remeron (Mirtazapine)

Overview
Remeron is a prescription drug approved by the Food and Drug Administration (FDA) to treat depression in adults. Remeron is also referred to by its drug name, Mirtazapine.

Remeron is an atypical… read more

Rexulti (Brexpiprazole)

Overview
Rexulti is a prescription drug approved by the Food and Drug Administration (FDA) as an adjunctive (add-on) therapy to antidepressants for treating major depressive disorder. Rexulti is also known by its drug… read more

Risperdal (Risperidone)

Overview
Risperdal is a prescription drug approved by the Food and Drug Administration (FDA) for the treatment of manic or mixed episodes associated with bipolar I disorder. Risperdal is also known by its drug name,… read more

Risperdal Consta (Risperidone)

Overview
Risperdal Consta is a prescription drug approved by the Food and Drug Administration (FDA) for maintenance treatment of bipolar I disorder. Risperdal Consta is also known by its drug name, Risperidone.… read more

Ritalin (Methylphenidate)

Overview
Ritalin is a prescription drug approved by the Food and Drug Administration (FDA) to treat narcolepsy and attention deficit disorders. Ritalin is sometimes prescribed to treat depression. Since the FDA has not… read more

Saphris (Asenapine)

Overview
Saphris is approved by the U.S. Food and Drug Administration (FDA) for the treatment of schizophrenia in adults and for the treatment of bipolar 1 disorder in both adults and children aged 10 to 17. For bipolar 1…

Savella (Milnacipran)

Overview
Savella is a prescription drug approved by the Food and Drug Administration (FDA) to treat fibromyalgia. Savella is sometimes prescribed to treat depression. Since the FDA has not approved Savella specifically… read more

Seroquel XR (Quetiapine)

Overview
Seroquel XR is a prescription drug approved by the Food and Drug Administration (FDA) for the treatment of bipolar disorder and some types of depression. Seroquel XR is also known by its drug name, Quetiapine.… read more

Spravato (Esketamine)

Overview
Spravato is a prescription drug approved by the U.S. Food and Drug Administration (FDA) for the treatment of adults with treatment-resistant depression (TRD), either alone or in combination with an oral…

Tegretol (Carbamazepine)

Overview
Tegretol is a prescription drug approved by the Food and Drug Administration (FDA) to treat trigeminal neuralgia and some types of seizures. Tegretol is sometimes prescribed to treat certain types of… read more

Topamax (Topiramate)

Overview
Topamax is a prescription drug approved by the Food and Drug Administration (FDA) to treat epilepsy and migraines. Topamax is sometimes prescribed to treat depression. Since the FDA has not approved Topamax… read more

Transcranial magnetic stimulation (TMS)

Overview
Transcranial magnetic stimulation (TMS) is a medical procedure sometimes used to treat severe cases of depression that don’t respond to therapy or medication. TMS may also be considered as treatment for… read more

Trazodone

Overview

Trazodone is approved by the U.S. Food and Drug Administration (FDA) for the treatment of major depressive disorder (MDD). It is not recommended for children under 18 due to an increased risk of suicidal thoughts…

Trintellix (Vortioxetine)

Overview
Trintellix is a prescription drug approved by the Food and Drug Administration (FDA) to treat major depressive disorder. Trintellix is also referred to by its drug name, Vortioxetine. Trintellix was previously… read more

Valium (Diazepam)

Overview
Valium is a prescription drug approved by the Food and Drug Administration (FDA) to treat anxiety. Valium is also known by its drug name, Diazepam.

Valium is an anxiolytic (antianxiety medication) of the… read more

Viibryd (Vilazodone)

Overview
Viibryd is a prescription drug approved by the Food and Drug Administration (FDA) to treat major depressive disorder. Viibryd is also referred to by its drug name, Vilazodone.

Viibryd is an atypical… read more

Vivactil (Protriptyline) for Depression

The Vivactil brand name has been discontinued in the U.S. for reasons unrelated to safety or efficacy. Other brand names or generic alternatives may be available. If you’re currently taking this medication, talk to your… read more

Vraylar (Cariprazine)

Overview
Vraylar is approved by the U.S. Food and Drug Administration (FDA) for the treatment of schizophrenia in adults. It is also approved for the acute treatment of manic or mixed episodes and depressive episodes…

Wellbutrin (Bupropion)

The Wellbutrin brand name has been discontinued in the U.S. Other brand name or generic alternatives may be available.

Overview

Wellbutrin is a prescription drug approved by the Food and Drug Administration (FDA) to…

Wellbutrin SR (Bupropion Hydrochloride)

Overview

Wellbutrin SR is approved by the U.S. Food and Drug Administration (FDA) for the treatment of major depressive disorder (MDD). It is intended for use in adults and is not approved for children. Wellbutrin SR…

Wellbutrin XL (Bupropion Hydrochloride)

Overview

Wellbutrin XL is approved by the U.S. Food and Drug Administration (FDA) for the treatment of major depressive disorder (MDD) and for the prevention of seasonal affective disorder (SAD). For individuals with MDD…

Xanax (Alprazolam)

Overview
Xanax is a prescription drug approved by the Food and Drug Administration (FDA) to treat anxiety. Xanax is also known by its drug name, Alprazolam.

Xanax is an anxiolytic (antianxiety medication) of the… read more

Zoloft (Sertraline)

Overview
Zoloft is a prescription drug approved by the Food and Drug Administration (FDA) to treat major depressive disorder in adults. Zoloft is also known by its drug name, Sertraline.

Zoloft is an antidepressant… read more

Zulresso (Brexanolone)

The Zulresso brand name has been discontinued in the U.S.

Overview
Zulresso is approved by the U.S. Food and Drug Administration (FDA) for the treatment of postpartum depression (PPD) in people 15 and older. As of July…

Zurzuvae (Zuranolone)

Overview
Zurzuvae is approved by the U.S. Food and Drug Administration (FDA) to treat postpartum depression in adults. It’s prescribed for people experiencing depression after childbirth. Zurzuvae can be taken by itself…

Zyprexa (Olanzapine)

Overview
Zyprexa is a prescription drug approved by the Food and Drug Administration (FDA) for the treatment of schizophrenia. Zyprexa is sometimes prescribed to treat depression that has failed to respond to… read more