SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITOR (SNRI)
Savella is a prescription drug approved by the Food and Drug Administration (FDA) to treat fibromyalgia. Savella is sometimes prescribed to treat depression. Since the FDA has not approved Savella specifically for this usage, it is considered “off-label.” Savella is also known by its drug name, Milnacipran.
Savella is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. Savella is believed to work by changing the balance of neurotransmitters in the brain.
How do I take it?
Savella is taken twice daily.
Savella comes in tablet form.
The FDA-approved label for Savella lists common side effects including headache, dizziness, insomnia, flushing, dry mouth, nausea, vomiting, increased sweating, and heart palpitations.
Rare but serious side effects listed for Savella include worsening depression, suicidal thoughts, serotonin syndrome, liver problems, glaucoma, abnormal bleeding, seizures, and elevated blood pressure and heart rate.
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Savella – Actavis