After years of changing many antidepressants and maxing them and adding to them with no results, I am weaning off the three I was currently on...I am going to try mushrooms...my son has had success with them...fyi.... cymbalta withdrawal sucks!

Each person's body and brain are different. You may have to try a lot or combinations of meds (cocktail) before things work. Be patient. Hang in there.

Hello Hayley, normally the first antidepressant (AD) the doctors prescribe you is the one they do with others as well, but it might not be suitable for you, so they keep trying or refer you to a psychiatrist who also has their favourite AD.
I've tried over 6 AD's none them helped me and caused too many side-effects until finally the doctor chose one I've been on for 20 years.

over 20 some years I've tried over 16.. some people have "treatment resistant depression" and require radical treatments.. I keep up with the research, and the truth is scientist really aren't any closer to a cure than they've been in years.. It's great if you have a Dr. that's willing to look down other avenues for some possible relief. alot of it may require some footwork on your part to find something that might work..

That’s good anything is a bonus