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Real members of MyDepressionTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyDepressionTeam Member asked a question 💭
Not telling

I am non binary she/her. I have chest dysmorphia for the most part. I also have PCOS with irregular periods and I don't want them I don't think any women really enjoy them. My firmer doctor told me last year after having an ovary and tube removed that I may get them I may not. My new doctor knows about the surgery but is worried I have t had one in six months. She put me on progesterone and it can make longer and more painful periods.t hey usually last three or four fays.I feel so disconnected… read more

December 3, 2025
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A MyDepressionTeam Member

I feel for you but don't understand it. I know and believe in the Jung analysis of anima and animus because we all are genetically mixed and produce certain hormones. The degree of male female is determined by how much flow in utero - I think. This means that despite the machismo or hyper feminine antagonists, the variety in humans is quite real. The hang-up on sex is absurd but real. They can't accept it but too bad.

When it comes to biology, biochemistry and altering one's development, I'm on shaky ground. I can say that transhumanism and augmentation is a real possibility and one that is a good thing. In a separate vein, we have cochlear ears, deep vagus nerve stimulation, artificial hearts, pace makers, and even control of limbs by the brain via wireless for paralyzed people. We alter disruptive heartbeats through medicine, as you know Metformin's functions and psychotropics to help restore normalcy of function on a daily basis.

So now to your suffering. I don't have an answer accept that progress may be slow in coming. Current technology and pharmacology may be in its infancy and there is simply no way around the changes. But they will come. Feeling disgusted in your own body may be an inevitable part of transformation and if we were conscious in a cocoon transforming to a butterfly but had to undergo total change, we might feel...discomfort. Instead of the moth in stasis, your cognizant of the change.

I hope the bad symptoms go away and a gradual realization of a new you will be forthcoming. It sounds insensitive and trite but maybe such changes are inevitable for the body that already has a sense of equilibrium but is now being altered. The body is rebelling for now.

December 3, 2025
MyDepressionTeam

How can you manage the anxiety and emotional disconnection from multiple new medications, especially when progesterone may worsen menstrual symptoms?

It's completely understandable to feel tired, anxious, and overwhelmed when dealing with multiple medications that may worsen symptoms you're already struggling with. The Show Full Answer

How can you manage the anxiety and emotional disconnection from multiple new medications, especially when progesterone may worsen menstrual symptoms?

It's completely understandable to feel tired, anxious, and overwhelmed when dealing with multiple medications that may worsen symptoms you're already struggling with. The emotional burden of these changes is real, especially when they affect how you feel connected to your body.

Regarding progesterone and depression, it's important to know that progesterone can affect mood in complex ways. Research shows mixed results - some studies suggest it may help with mood, while others indicate it can potentially worsen depressive symptoms. If you notice increased feelings of disconnection, disgust, or worsening depression after starting progesterone, it's crucial to communicate this with your doctor.

Here are some things to monitor:

• Changes in your mood or anxiety levels after starting progesterone
• Increased feelings of disconnection or disgust with your body
• Any new or worsening depressive symptoms
• How the combination of medications affects your overall mental health

The anxiety you're experiencing about these medical changes is valid. When managing depression alongside other health concerns, the stress of treatment itself can feel overwhelming. Consider discussing with your doctor whether all these medications need to start simultaneously, or if a gradual approach might reduce your anxiety.

If you have a therapist or counselor, this would be an important time to check in about the emotional impact of these changes. They can help you process the feelings of disconnection and develop coping strategies while you navigate these treatments.

Remember that you have the right to advocate for your mental health needs alongside your physical health needs. If a medication is significantly worsening your depression or anxiety, that's important medical information your doctor needs to know.

December 3, 2025

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