Drizalma Sprinkle (Duloxetine) for Depression

Overview

Drizalma Sprinkle is approved by the U.S. Food and Drug Administration (FDA) for the treatment of major depressive disorder (MDD) in adults.Drizalma Sprinkle is also known by its drug name, duloxetine.

Drizalma Sprinkle is a serotonin and norepinephrine reuptake inhibitor (SNRI). It works by increasing the levels of the neurotransmitters serotonin and norepinephrine in the brain, which are thought to play a role in regulating mood.

How do I take it?

Prescribing information states that Drizalma Sprinkle may be taken with or without food. It can be swallowed whole, opened and sprinkled over applesauce, or administered via a nasogastric tube. For MDD in adults, a dose is either taken once daily or split into two doses. The drug should be taken exactly as prescribed by a healthcare provider.

Side effects

Common side effects of Drizalma Sprinkle include nausea, dry mouth, somnolence (drowsiness), constipation, decreased appetite, and hyperhidrosis (excessive sweating).

Rare but serious side effects may include suicidal thoughts and behaviors (particularly in young adults and children), liver damage, serotonin syndrome (a potentially life-threatening condition caused by too much serotonin), severe skin reactions such as Stevens-Johnson syndrome, high blood pressure, seizures, hyponatremia (low sodium levels), increased bleeding risk, activation of mania or hypomania, and glaucoma due to increased eye pressure. Sexual dysfunction is also a potential side effect.

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Label: Drizalma Sprinkle — Duloxetine Capsule, Delayed Release — DailyMed