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Real members of MyDepressionTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I have Bioplar 1 Disorder and asked to be discontinued from it cuz I was experiencing a lot of side effects such as weight gain, extreme hunger, extreme thirst, and my blood levels increased

October 13, 2025
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A MyDepressionTeam Member

I just started it. My Dr. Did talk about the metabolic side effects but said the Mounjaro I am on actually counteracts the issues. Win win!

October 14, 2025
A MyDepressionTeam Member

I’m on Abilify and have gained some weight. I have also been on oral steroids for a neck injury. My psychiatrist said the combo probably made it worse I’m trying to lose weight before I see him in a month because the medication works well for me and I don’t want it stopped.

October 13, 2025
MyDepressionTeam

Weight gain and metabolic changes are common side effects with antipsychotic medications used to treat depression. Many people experience similar challenges with increased appetite, thirst, and changes in blood levels. While frustrating, these are known side effects that should be monitored by your healthcare provider.

Show Full Answer

Weight gain and metabolic changes are common side effects with antipsychotic medications used to treat depression. Many people experience similar challenges with increased appetite, thirst, and changes in blood levels. While frustrating, these are known side effects that should be monitored by your healthcare provider.

Some common side effects of antipsychotic medications include:
• Weight gain
• High blood pressure
• High blood sugar
• Drowsiness
• Low energy It's important to discuss medication concerns with your doctor rather than stopping treatment on your own. They may be able to:
• Adjust your dosage
• Switch you to an alternative medication
• Help develop strategies to manage side effects

Some members find success in counteracting weight gain through diet and exercise while continuing their medications. As one member shared, working with a personal trainer helped them manage medication-related weight gain while maintaining their mental health benefits.

October 13, 2025
A MyDepressionTeam Member
October 18, 2025
A MyDepressionTeam Member

I have a pill organizer for both morning and nighttime meds and I can barely get anymore into the morning side and the p.m. side is damn close to full. and it's NOT a small pill organizer...

I feel you, @A MyDepressionTeam Member, I hate having to rely on all these meds...

October 18, 2025

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