I take Zoloft 50mg in the morning and anouther 25mg at supper. I also have 1mg of Lorazapam for night if needed. I find now that I am taking the 2 Zolofts a day it is working well

I take 50mg too but dr said when grandma passes that she might up it too 100mg. So ur saying the 100 doesn't help either? 50 is helping me sleep better. Before I started taking it, I was going to bed every night then waking up to a fainting spell which I guess is called an anxiety attack. Zoloft lets me sleep all night now. Thank goodness. I have been taking it for a couple of years now.

I take 2x 100mg each morning with a concoction of other medication due to my disability. This helps me physically and enables me to get on with my job. I was previously prescribed Citalopran which did not help me.

I am also on sertraline. Started at 50 then 100. It does nothing for me. It made me lose my sex drive and appetite. As my deppresion is very bad at times to the extent of falling behind with my bills and locking myself away. Missed so many appointments that i really need to make the effort to get back to my doctors to get sorted .

I have been on Sertraline 2 x 100mcg taken first thing in the morning for a few years now and was previously onin citalopran for many years which became ineffective. Not been a good year at all and can’t wait until I see this horrible year end. However, I have been saying the same thing now for many years just hoping each year will be better than the last one.