Yes, I'm on meds and supplements and transitioning from Spravato to micro-dosing Ketamine next week. Also, started on Auvelity a month back. Unfortunately, Spravato only worked a bit, not enough to help me be a productive person though. I still have hope. I know, in my heart, that it will not always be like this...no matter how much despair I feel at times. New meds hit the public every day, I'm hopeful for the Ketamine pill or MDMA treatments that will be available soon. We just gotta take it moment by moment and hang in there (even if it's a slow sloth-like hang).

You can do this, you are a survivor and courageous. Best wishes to you and all of us!

It took me almost 20 years to get the correct medication at the right dose for me as I was prescribed 100mg of sertraline back in October 2018 as that's when my late dad got his terminal cancer diagnosis and lost his short but brave battle with terminal lung cancer due to smoking cigarettes the following March. It's 5 years this year since my nanna came for my daddy (that's how my mum told me that my daddy had passed away and it's also how I like to remember it) and my antidepressants are still doing their job. My daddy was only 63 years old.
I'm a nanna's and daddy's girl and I always will be. I'm in my early 40s.

I was diagnosed with mixed bipolar rapid cycling about 4 years ago, the first 3 1/2 of those years was spent trying to find medication that "worked" for me. Worst part of that is dosing up and down on so many different combinations of medication can have MANY horrible side effects in itself. There were many moments in that time where I was worse off than before the meds ( as impossible as that had seemed at the time)
Over 3 years of non stop changing and messing with the natural chemicals in my brain.... It's HELL!!! I wrote numerous suicide notes over that time, and no "I'm sorry" crap ... I had the password to my phone for my roommate to get to my personal numbers, I apologized to her for anything finding me may do to her or the scars it would leave her with for the rest of her life. Most of them looked more like a final will... What to do with my cat ect.
I still have all of thos notes today. My psych team all pretty much agreed that they don't think I should have them... But I keep them anyway because they are the one thing that saved my life (over and over) by reading how me leaving would or could potentially affect so many others... Knowing that there are people I care about, that care about me, some even rely on me... What it would do to them if I decided to leave... I can't do that to them.
Today I'm grateful for those notes that saved my life. I'm on a cocktail of medications that seem to helping... I still have a long way to go before I can even apply for a job and work again... But anything is better than the hell I was in.
I guess what I'm saying is the only thing that saved or helped me on my literal rollercoaster through hell was hope. And for a non religious person that's hard to find. Every day I wake up and take my pills and while in the shower I try and fill every moment spent in there thinking of things I SHOULD be grateful for... Some days in order to fill the time I'm in there the thing I find are so small and silly but we tend to take what we do have for granted and make focusing on the things we don't have or the negative. I'm trying to train my brain to look the other way... And it has helped me in many ways, especially with keeping bonds with family while in my low states. I also have been trying mindfulness.... It can be really hard at first but it gets easier the more you do it, and I actually quite enjoy it now. We will even do silly things like look for a specific color on our walks and see you can point out more things. Anything to keep you looking outwards and appreciation for what's around you can stop you for getting stuck within... Im not "cured" or "normal" by any means.... But normal is boring anyhow... I'm better than I was and I am finding ways to cope and dare I say find moments of happiness or contentment, and I'll always have room to grow....
One step at a time... It's only one step. ❤️

I’ve changed my medicine many times cuz the effect wore off- not improved my depression.

I feel the same way!