I was on Effexor for almost a year about 18 years ago. It pulled me out of a severe depression but I never adjusted to the side effects. On the other hand, a relative of mine took it for years without any side effects at all. These things are highly individual.

I have been on Effexor xr 300mg for over 20 yrs and haven’t had anything bad occur. It’s the only drug I have found to continue to work. All the others seem to lose their purpose within and year.

I'm currently taking effexor. What side effects are you experiencing?

Years ago I came off an extremely high dose it took a little while then I felt the effects lessen till I didn't notice them anymore

I took that medication for a few years 2 different times