I think so. I mean hormones and emotions out of whack and we already have issues. Lol. I say it can make both worse.

I talked to my doctor and she said it's common. Personally it's suicidal ideology for me. So she upped my dosages during that time period

When I get my period, it's a relief because my PMS is so horrible. I was under the impression that my PMS symptoms would get better with age, but I have found the opposite, and, much to my dismay, my depression and anxiety are much worse when I'm PMSing, also worse with age. Especially the anxiety, along with irritability, doubled. Better to stay away from everybody and everything for 2 weeks a month. Which adds to my depression. It's a vicious cycle, at least for me. 😣

My meds control my fatigue. Without medication I sleep too much